Association between gastric acid suppressants and Clostridium difficile colitis and community-acquired pneumonia: analysis using pharmacovigilance tools

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منابع مشابه

Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease.

CONTEXT Recent reports suggest an increasing occurrence and severity of Clostridium difficile-associated disease. We assessed whether the use of gastric acid-suppressive agents is associated with an increased risk in the community. OBJECTIVE To determine whether the use of gastric acid-suppressive agents increases the risk of C difficile-associated disease in a community population. DESIGN,...

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Klebsiella pneumonia septic shock and death in a patient with community- acquired Clostridium difficile colitis (CA-CDI):

acquired Clostridium difficile colitis (CA-CDI): Orville D. Heslop, Karen RoyeGreen, Kathleen Coard, and Michael R. Mulvey Department of Microbiology, University of the West Indies, Jamaica, Department of Pathology, University of the West Indies, Jamaica, National Microbiology Laboratory 1015 Arlington St. Winnipeg, MB R3E 3R2 Abstract Background: Clostridium difficile is the major cause of no...

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Community-Acquired Clostridium difficile Infection, Queensland, Australia

in the case-patient’s family or the community. On the basis of a matching surname, case-patient E was determined to be a member of the same family as case-patients P20, P26, and likely C. Soft tissue infection was documented in all 5 casepatients, supporting the original observation that ST2371 is associated with disease. Evidence of familial transmission in the original outbreak is further sup...

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Association between Obstructive Sleep Apnea and Community-Acquired Pneumonia

BACKGROUND We hypothesized that obstructive sleep apnea (OSA) can predispose individuals to lower airway infections and community-acquired pneumonia (CAP) due to upper airway microaspiration. This study evaluated the association between OSA and CAP. METHODS We performed a case-control study that included 82 patients with CAP and 41 patients with other infections (control group). The controls ...

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Association Between Appendectomy and Clostridium difficile Infection

BACKGROUND Recent theory proposes that the appendix functions as a reservoir for commensal bacteria, and serves to re-inoculate the colon with normal flora in the event of pathogen exposure or purging of intestinal flora. If true, we reasoned that flora from a normal appendix could provide protection against Clostridium difficile. We conducted this investigation to examine the protective effect...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2007

ISSN: 1201-9712

DOI: 10.1016/j.ijid.2006.11.004